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TD Trans D Base


Trans D cream base, is an oil-in-water emulsion, which is an ideal compounding vehicle for topical delivery of a broad range of APIs such as corticosteroids, anti-bacterial, anti-fungal, anesthetic and exfoliating agents. It can also be used for alleviating dry skin.

Available Sizes:

100G, 500G

Where to buy

Trans D cream base, is a white non greasy O/W emulsion base. It is suitable for topical delivery of a wide variety of APIs such as corticosteroids, anti-bacterial, anti-fungal, anesthetics and exfoliating agents. It can also be used for alleviating dry skin.


  • Eczema/Dermatitis
  • Skin whitening (depigmenting)
  • Anti-bacterial
  • Anti-Fungal
  • Anti-aging

API Compatibility Chart


Common Concentration (s)


Common Concentration (s)

Aloe Vera Extract

2 to 10%

Lactic Acid

1 to 15%

Azelaic Acid



10 to 20%

Lidocaine Hal

0.5 to 10%

Benzoyl Peroxide

2 to 5%


1 to 3%

Betamethasone dipropionate

0.025 to 0.1%

Retinoic Acid (Tretinoin)

0.01 to 0.1%

Betamethasone Valerate

0.025 to 0.1%

Salicylic Acid

1 to 5%


1 to 2%


2.5 to 5%

Clindamycin Phosphate

1 to 4 %

Tocopherol (Vit E)

0.5 to 4%

Clobetasol propionate

0.025 to 0.05%

Triamcinolone Acetonide

0.025 to 0.1%


1 to 2 %


1 to 5%

Cyanocobalamine (B12)

0.05 to 0.1%

Zinc Oxide

1 to 5%


0.05 to 0.1%





1 to 4 %


0.1 to 2 %

Flucinolone acetonide

0.01 to 0.1%

Tea tree

0.1 to 2 %

Glycolic Acid

5 to 10%

Aloe vera

0.1 to 2 %


0.5 to 3%

Cannabinoid Isolates & Distillate

0.1 to 10%


1 to 2 %

Vitamin C

5 to 10%

Kojic Acid

1 to 4 %


***The above recommended concentrations are for transdermal application. The concentration is required to be adjusted for any other route of administration such as mucosal, vaginal or rectal delivery.


 Examples of compounding formulations with Trans D Base

Retinoic Acid 0.05% HQ 4% in Trans D Base

Desonide 0.05% HQ 4% in Trans D Base

Retinoic Acid 0.1% in Trans D Base

Metronidazole 2% in Trans D Base

Erythromycin 2% in Trans D Base

Lidocaine 2% in Trans D Base


Compounding tips

Recommended wetting agents for levigation; glycerin, propylene glycol, mineral oil, MCT oil and water.


Trans D Physicochemical Characteristics


 4 – 6


 20,000 – 40,000 CPS



 Dosage Form  




Disclaimer: Transderma Pharmaceuticals Inc. has provided the formula and instructions above as a model for educational purposes only on the basis of recognized compendia and texts or references. Transderma Pharmaceuticals Inc. takes no responsibility for the validity or accuracy of this information or for its safety or effectiveness, nor for any use thereof, which is at the sole risk of the licensed pharmacist. Adjustments may be needed to meet specific patient needs and in accordance with a licensed prescriber’s prescription. The pharmacist must employ appropriate tests to determine the stability of this suggested formula. Transderma Pharmaceuticals Inc., its owners, officers, agents, contractors, affiliates and employees cannot be held liable to any person or entity concerning claims, loss or damage caused by, or alleged to be caused by, directly or indirectly, the use or misuse of the information contained in this suggested formula. In all cases, it is the responsibility of the licensed pharmacist to know the law, to compound any finished product and to dispense these products in accordance with Health Canada and FDA guidelines and appropriate Provincial Drug Schedules and Provincial or Territorial Pharmacy Practice Standards.

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