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Transderma PLO Gel

Introduction

Transderma PLO (Premium Lecithin Organogel) represents the next generation of PLO gels. Transderma PLO Premixed Gels are ready-to- use intradermal bases. Intradermal bases are the mainstay of Local Enhanced Transdermal Delivery.

Available Sizes:

100g, 500g and 2Kg

Where to buy

Transderma PLO (Premium Lecithin Organogel) represents the next generation of PLO gels. Transderma PLO Premixed Gels are ready-to- use intradermal bases. Intradermal bases are the mainstay of Local Enhanced Transdermal Delivery. LETD, for example, is an effective, safe alternative to oral NSAID use for local tissue inflammation. Transderma PLO Gels are specially made to target local tissues and achieve local therapeutic drug-levels while minimizing blood-level related toxicities. 

PLO gels have already gained acceptance as the intradermal vehicle of choice for a variety of drugs including diclofenac, ibuprofen, ketoprofen, and progesterone. The benefits of Transderma PLO Gels include: 

  1. High Penetrating-Power – Achieve high, therapeutic tissue-levels while reducing blood-level related side effects
  2. Ready-to-Use – Reduce compounding time
  3. Improved Stability – Remain uniform and appealing for longer periods of time and under different storage conditions
  4. No skin-irritating pluronic surfactant ? Avoid local skin- intolerance reactions
  5. Cosmetically-Pleasing – a non-greasy, non-tacky, soothing skin moisturizer

CAN

Toll Free: 1.800.663.1002
Website: www.xenexlabs.com

 

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Corporate Head OfficeXenex has been supplying the highest quality products, delivered by qualified professionals to the Canadian compounding profession for over 30 years. Xenex focuses on the compounding pharmacist and has built a valuable set of support services to provide the pharmacist with education, formulation support and competitively priced product, delivered by a knowledgeable sales and customer services team.

Conventional wisdom states that oil and water do not mix – which pharmacists know not to be true. Formulated correctly, creams, ointments and gels can be prepared to bring these two phases together resulting in some of the most useful topical pharmaceutical preparations. 

PLO Gel represents a 2nd generation PLO gel which has an improved emulsification system resulting in a smoother, less viscous and tacky feel than traditional PLO gels. Importantly, the improvement in cosmetic feel is contained within this high quality GMP manufactured product, which has known penetration enhancing performance and good stability. Transderma Pharmaceuticals Inc. is committed to high quality products based on science with the patient in mind.

PLO Ultramax Gel is a ready to use intradermal base.
Its unique penetrating power makes an ideal vehicle to deliver therapeutic agents to sites within the skin.
Transderma facilitates the transport of therapeutic agents through the skin to reach other body tissues and fluids.
PLO gels have already gained acceptance as the vehicle of choice for the anti-inflammatory drug, diclofenac.
Drugs that may be frequently used by Transderma are:

Topical and Transdermal Drug Delivery

Evaluation Of Topical Non-Steroidal Drugs

Topically Applied NSAIDs In The Treatment Of Pain – coming soon

Topical Anti-Inflammatories: Role In Therapy – coming soon

Instructions for the incorporation of Drug. (Compounding)

The compounding may take place on an ointment slab or with the use of a mortar and pestle.
Mix the drug (powder) with a few drops of isopropyl Alcohol. Be sure not to use too much Alcohol. The resultant mix should be a smooth paste. (Not runny.)
Levigate the paste with a portion of the Transderma base to form a smooth nucleus.
Incorporate balance of the base by geometric dilution.
Continue to mix until the gel has re-formed into an even smooth, silky consistency.