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Transderma PLO Kits

Introduction

Tranderma PLO Kits are conveniently packed with three key components in separate bottles: Organic/Lecithin Isopropyl Palmitate Solution phase, Hydrophilic/Pluronic Gel phase, and Ethoxy Diglycol solvent.

Available Sizes:

100ml, 500ml, and 1000ml 500ml Hydrophilic/Pluronic Gel and 500ml Organic/Lecithin Isopropyl Palmitate Solution

Where to buy

Tranderma PLO Kits are conveniently packed with three key components in separate bottles: Organic/Lecithin Isopropyl Palmitate Solution phase, Hydrophilic/Pluronic Gel phase, and Ethoxy Diglycol solvent. When incorporated with the active ingredient in the desired proportions, the result is a unique PLO topical base that is tailored to patients requirement of drug concentration and degree of moisturization. 

The new PLO Kit now contains a Hydrophilic/Pluronic Gel phase with 30% pluronic. This enables the pharmacists to produce a more robust final gel product and uniquely deliver more active drug to the desired area. 

A Matter of Choice – The question of choosing between the use of the PLO Premixed Gel or the PLO Kit is a matter of personal preference. With the versatile PLO Kit, the finished product can be customized to meet the unique compounding needs of the prescription, yet is conveniently packed for ease of preparation by the pharmacist.

CAN

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Website: www.xenexlabs.com

 

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Corporate Head OfficeXenex has been supplying the highest quality products, delivered by qualified professionals to the Canadian compounding profession for over 30 years. Xenex focuses on the compounding pharmacist and has built a valuable set of support services to provide the pharmacist with education, formulation support and competitively priced product, delivered by a knowledgeable sales and customer services team.

Methods of Compounding Transderma and drug 

A finished product of drug incorporated in Transderma is prepared by compounding the prescribed amounts of Transderma Organic/Lecithin Isopropyl Palmitate Solution (A) and Transderma Hydrophilic/Pluronic Gel (B) with alcohol and drug to obtain the desired quantity ready for dispensing. 

  1. Disperse drug in alcohol in a mortar. Add to (A) and mix until uniformly dispersed or dissolved.
  2. Gradually incorporate (B) with the mixture of (A) and drug with vigorous trituration until gel is formed.

Recomendation 

  1. Store Transderma Organic/Lecithin Isopropyl Palmitate Solution at room temperature, and Transderma Hydrophilic/Pluronic Gel in the refrigerator. NOTE: Transderma Hydrophilic/Pluronic Gel is solid at room temperature, and liquefies at refrigerated temperature.
  2. Warm Transderma Hydrophilic to about 10°C prior to compounding to improve the rate of the gelling process.
  3. Thorough dispersion or dissolution of drug in Transderma Organic/Lecithin Isopropyl Palmitate Solution is important before incorporating Transderma Hydrophilic in order to obtain best results.
  4. If greater than 2% drug is used, reduce the alcohol content, to about 5%, to obtain a more coherent gel.

The proportions of materials to be used to make various quantities of Transderma containing 2% drug are outlined below: