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Products

TD TransPen Base

Introduction

Trans Pen is an oil-in-water vanishing cream formulated for enhanced transdermal delivery of hydrophilic and lipophilic APIs. This elegant alternative to PLO, with added natural emollients, provides a better spreadability and more sustained moisturizing effect without irritation.

Available Sizes:

100G, 500G

Where to buy

An oil-in-water vanishing cream for enhanced transdermal delivery of lipophilic and hydrophilic APIs. It contains natural emollients with more sustained skin moisturizing effect.

Trans Pen Highlighted Benefits

  • Cosmetically elegant
  • Non-tacky residue
  • Enhanced penetration of lipophilic and hydrophilic APIs
  • Sustained moisturizing effect
  • Paraben Free

Application

  • Pain management
  • HRT
  • Eczema/Dermatitis

API Compatibility Chart

API

Common Concentration (s)

API

Common Concentration (s)

Amitriptyline

0.5 to 2%

Ketoprofen

2 to 10%

Baclofen

1 to 5 %

Lidocaine

2 to 5%

Benzocaine

2 to 5 %

Menthol

1 to 5%

Buspirone

2.5 mg/ml

Methimazole

1 to 5%

Camphor

1 to 2%

Metoclopramide

1 to 2%

 

Capsaicin

 

0.75 to 1%

 

 

Metronidazole

1 to 2%

Clomipramine

5 to 7.5%          

Methyl Salicylate

5 to 10%

Cyclobenzaprine

0.5 to 2%

Nifedipine

0.5 to 10%

Dehydroepiandrosterone

1 to 2.5%

 

Piroxicam

5 to 10%

Diclofenac

2.5 to 10%

Pentoxiphyline

3 to 5%

Diltiazem

 

2 to 5%

Progesterone

1 to 5%

Estradiol

0.1 to 1 mg/ml

Promethazine

2.5 to 5%

Estriol

 

0.2 to 2 mg/ml

Sildenafil

 

1%

Gabapentin

 

6%

Tadalafil

0.2%

Ibuprofen

2 to 10%

Testosterone

0.5 to 2.5%

Ketamine

2 to 5%

Tetracaine

3 to 5%

***The above recommended concentrations are for transdermal application. The concentration is required to be adjusted for any other route of administration such as mucosal, vaginal or rectal delivery.

 

Essential Oil Compatibility Chart

Essential Oil

Common Concentration (s)

Essential Oil

Common Concentration (s)

Argan Oil

1 to 8%

Myrrh Essential Oil

1 to 3%

Eucalyptus Essential Oil

1 to 3%

Thyme Essential Oil

0.5 to 2%

Grapefruit Essential Oil

1 to 3%

Tea Tree  Essential Oil

1 to 5%

Lavender  Essential  Oil

1- 2.5%

 

 

Rose Hip  Essential Oil

0.5 to 3%

Jojoba Oil

1 to 10%

 

 

Peppermint  Essential Oil

1 to 3%

Winter Green Essential Oil

1 to 3%

Spearmint  Essential Oil

1 to 3%

 

Examples of compounding formulations with TD Trans Pen Base

Diclofenac 10% in Trans Pen

Diclofenac 7.5% Cyclobenzaprine 2% in Trans Pen

Progesterone 5% in Trans Pen

Diclofenac 5% Lidocaine 2% Ketamine 2% in Trans Pen

Gabapentin 6% Lidocaine  2% in Trans Pen

Metronidazole 2% in Trans Pen

Capsacin 0.05% Menthol 2% Methyl Salicylate 8% in Trans Pen

DHEA 25 mg/ml in Trans Pen

Methimazole 5% in Trans Pen

 

Compounding tips:

Ethoxy Diglycol, Glycerin, MCT oil, Mineral oil or Propylene Glycol are recommended as levigating agent.

Trans Pen Physicochemical Characteristics

pH

6.5 – 6.8

Viscosity

30,000 – 75,000 CPS

Color

Sandlewood

Dosage Form

Cream

 

 

 

Disclaimer: Transderma Pharmaceuticals Inc. has provided the formula and instructions above as a model for educational purposes only on the basis of recognized compendia and texts or references. Transderma Pharmaceuticals Inc. takes no responsibility for the validity or accuracy of this information or for its safety or effectiveness, nor for any use thereof, which is at the sole risk of the licensed pharmacist. Adjustments may be needed to meet specific patient needs and in accordance with a licensed prescriber’s prescription. The pharmacist must employ appropriate tests to determine the stability of this suggested formula. Transderma Pharmaceuticals Inc., its owners, officers, agents, contractors, affiliates and employees cannot be held liable to any person or entity concerning claims, loss or damage caused by, or alleged to be caused by, directly or indirectly, the use or misuse of the information contained in this suggested formula. In all cases, it is the responsibility of the licensed pharmacist to know the law, to compound any finished product and to dispense these products in accordance with Health Canada and FDA guidelines and appropriate Provincial Drug Schedules and Provincial or Territorial Pharmacy Practice Standards.

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Website: www.xenexlabs.com

Xenex has been supplying the highest quality products, delivered by qualified professionals to the Canadian compounding profession for over 30 years. Xenex focuses on the compounding pharmacist and has built a valuable set of support services to provide the pharmacist with education, formulation support and competitively priced product, delivered by a knowledgeable sales and customer services team.