For more information1.800.263.0016
For more information1.800.263.0016
TD Ultramax Gel is a new generation of PLO gels with higher capacity to incorporate APIs. Transdermal delivery of APIs is effectively used for both acute and chronic therapy over the las decade. Therefore we designed a vehicle that meet the demand of varying percentages of APIs, and also pharmacists demand for time- efficient and uniform compounding. This base accommodates higher percentage of APIs beyond the range of basic PLO gels.
100G, 500G
Transderma PLO (Pluronic Lecithin Organogel) Ultramax gel answers the need for ready-to-use vehicles to incorporate higher percentages of active drugs, without disturbing the elegant nature or the efficacy of the gel.
PLO Ultramax Gel Highlighted Benefits
Application
API Compatibility Chart
|
API |
Common Concentration (s) |
API |
Common Concentration (s) |
|
Amitriptyline |
0.5 to 2% |
Ketamine |
2 to 5% |
|
Baclofen |
1 to 5 % |
Ketoprofen |
5 to 10% |
|
Benzocaine |
2 to 5 % |
Lidocaine |
2 to 10% |
|
Buspirone |
2.5 mg/ml |
Menthol |
1 to 10% |
|
Camphor |
1 to 2% |
Methyl Salicylate |
5 to 10% |
|
Capsaicin
|
0.75 to 1%
|
Nifedipine |
0.5 to 10% |
|
Cyclobenzaprine |
0.5 to 2% |
Piroxicam |
5 to 10% |
|
Dehydroepiandrosterone |
1 to 2.5%
|
Pentoxiphyline |
3 to 5% |
|
Diclofenac |
2.5-10% |
Progesterone |
1 to 5% |
|
Diltiazem
|
2 to 5% |
Promethazine |
2.5 to 5% |
|
Estradiol |
0.1 to 1 mg/ml |
Sildenafil
|
1% |
|
Estriol
|
0.2 to 2 mg/ml |
Tadalafil |
0.2% |
|
Fluoxetine |
5 to 7.5% |
Testosterone |
0.5 to 2.5% |
|
Gabapentin
|
6% |
Tetracaine |
3 to 5% |
|
Ibuprofen |
5 to 10% |
***The above recommended concentrations are for transdermal application. The concentration is required to be adjusted for any other route of administration such as mucosal, vaginal or rectal delivery.
Examples of compounding formulations with TD Ultramax Base
|
Diclofenac 10% in Ultramax PLO Gel |
Diclofenac 7.5% Cyclobenzaprine 2% in Ultramax PLO Gel |
Progesterone 5% in Ultramax PLO Gel |
|
Diclofenac 5% Lidocaine HCl 2% Ketamine 2% in Ultramax PLO Gel |
Gabapentin 6% Lidocaine 2% in Ultramax PLO Gel |
Ketoprofen 10% in Ultramax PLO Gel |
Compounding tips:
Ethoxy Diglycol, Glycerin, Mineral oil or Propylene Glycol are recommended as levigating agent.
|
pH |
6 to 8 |
|
Viscosity |
200,000 to 400,000 CPS |
|
Color |
Ivory |
|
Dosage Form |
Gel |
Disclaimer: Transderma Pharmaceuticals Inc. has provided the formula and instructions above as a model for educational purposes only on the basis of recognized compendia and texts or references. Transderma Pharmaceuticals Inc. takes no responsibility for the validity or accuracy of this information or for its safety or effectiveness, nor for any use thereof, which is at the sole risk of the licensed pharmacist. Adjustments may be needed to meet specific patient needs and in accordance with a licensed prescriber’s prescription. The pharmacist must employ appropriate tests to determine the stability of this suggested formula. Transderma Pharmaceuticals Inc., its owners, officers, agents, contractors, affiliates and employees cannot be held liable to any person or entity concerning claims, loss or damage caused by, or alleged to be caused by, directly or indirectly, the use or misuse of the information contained in this suggested formula. In all cases, it is the responsibility of the licensed pharmacist to know the law, to compound any finished product and to dispense these products in accordance with Health Canada and FDA guidelines and appropriate Provincial Drug Schedules and Provincial or Territorial Pharmacy Practice Standards.
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Xenex has been supplying the highest quality products, delivered by qualified professionals to the Canadian compounding profession for over 30 years. Xenex focuses on the compounding pharmacist and has built a valuable set of support services to provide the pharmacist with education, formulation support and competitively priced product, delivered by a knowledgeable sales and customer services team.